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Okadaic acid

PP1 and PP2A inhibitor

Product Specifications

Background

Okadaic acid is a potent and selective inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A). Okadaic acid is a naturally occurring polyether toxin that was originally derived from marine dinoflagellates, Prorocentrium spp.. It is a reversible inhibitor.

CAS Number

78111-17-8

Product Name Alternative

9,10-Deepithio-9,10-didehydroacanthifolicin

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling

Purity

≥98% (HPLC)

Weight

0.00002

Format

White crystalline solid

Solubility

Soluble in chloroform, ethanol, methanol, acetone or ethyl acetate

Molecular Formula

C44H68O13

Molecular Weight

805

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Cohen P., Holmes C.F., & Tsukitani Y. (1990) Trends Biochem. 15(3): 98–102.

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