Okadaic acid
PP1 and PP2A inhibitor
Product Specifications
Background
Okadaic acid is a potent and selective inhibitor of protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A). Okadaic acid is a naturally occurring polyether toxin that was originally derived from marine dinoflagellates, Prorocentrium spp.. It is a reversible inhibitor.
CAS Number
78111-17-8
Product Name Alternative
9,10-Deepithio-9,10-didehydroacanthifolicin
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling
Purity
≥98% (HPLC)
Weight
0.00002
Format
White crystalline solid
Solubility
Soluble in chloroform, ethanol, methanol, acetone or ethyl acetate
Molecular Formula
C44H68O13
Molecular Weight
805
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Cohen P., Holmes C.F., & Tsukitani Y. (1990) Trends Biochem. 15(3): 98–102.
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