Ruxolitinib
JAK kinase inhibitor
Product Specifications
Background
Ruxolitinib is a Janus-associated kinases (JAK) inhibitor, which specifically inhibits JAK1 and JAK3. JAKs are known to active the signaling of certain growth factor receptors and cytokines.
CAS Number
941678-49-5
Product Name Alternative
(3R) -3- (4- (7H-pyrrolo[2,3-d]pyrimidin-4-yl) -1H-pyrazol-1-yl) -3-cyclopentylpropanenitrile
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98%
Weight
0.025
Format
Off-white solid
Solubility
Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml)
Molecular Formula
C17H18N6
Molecular Weight
306.4
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Aittomäki S., & Pesu M. (2014) Basic & Clin. Pharm.Toxic. 114(1): 18–23.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB1373-100 1x 100 µL
Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) (EGP40/1373), 0.2mg/mL
Sign In for Pricing
View Details 
![Junctophilin-2 Mouse Monoclonal Antibody [3-2]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea815ee/imageurl/m0407-20.webp)
![CD99 Rabbit Monoclonal Antibody [Clone ID: R06-8G3]](https://cdn.genprice.uk/products/937/68dd1b60061270361ea12305/imageurl/ta421619.webp)
TA421619 100 µL
CD99 Rabbit Monoclonal Antibody [Clone ID: R06-8G3]
Sign In for Pricing
View Details 
