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Indirubin-3'-monoxime

GSK, CDK kinase inhibitor

Product Specifications

Background

Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).

CAS Number

160807-49-8

Product Name Alternative

Indirubin-3'-monoxime, 3-[1,3-Dihydro-3- (hydroxyimino) -2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98% (HPLC)

Weight

0.005

Format

Red solid

Solubility

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Molecular Formula

C16H11N3O2

Molecular Weight

277.3

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.

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