Indirubin-3'-monoxime
GSK, CDK kinase inhibitor
Product Specifications
Background
Indirubin-3'-monoxime is an inhibitor of protein kinases and cyclin-dependent kinases. Specifically, it is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β).
CAS Number
160807-49-8
Product Name Alternative
Indirubin-3'-monoxime, 3-[1,3-Dihydro-3- (hydroxyimino) -2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.025
Format
Red solid
Solubility
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Molecular Formula
C16H11N3O2
Molecular Weight
277.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Damiens E., Baratte B., Marie D., Eisenbrand G., & Meijer L. (2001) Oncogene. 20(29): 3786–3797.
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