BRD 7389
P90 RSK kinase inhibitor
Product Specifications
Background
BRD 7389 is a p90 ribosomal S6 kinase (RSK) inhibitor. Specifically, BRD7398 inhibits RSK1, RSK2 and RSK3. This compound has been seen to unregulate insulin expression in terminally differentiated pancreatic &alpha-cells.
CAS Number
376382-11-5
Product Name Alternative
BRD7389, BRD-7389, 1-[ (2-Phenylethyl) amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione, 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.005
Format
Orange powder
Solubility
Soluble to 100 mM in DMSO
Molecular Formula
C24H18N2O2
Molecular Weight
366.4
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Fomina-Yadlin D., et al. (2010) Pro. Nat. Acad.Sci. USA. 107(34): 15099–15104.
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