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AZD6244

ERK kinase inhibitor

Product Specifications

Background

AZD6244 is a MEK-1 inhibitor. Specifically, AZD6244 inactivates the phosphorylation of ERK1/2.

Product Name Alternative

Selumetinib, AZD6244, 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

UNSPSC

41116105

Source

Synthetic

Purity

≥98%

Weight

0.005

Format

White to off-white solid

Solubility

Soluble in DMSO (92 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C)

Molecular Formula

C17H15BrClFN4O3

Molecular Weight

457.7

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Haasbach E., Hartmayer C., & Planz O. (2013) Antiviral Research. 98(2): 319–324.

CAS Number

606143-52-6

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