AZD6244

AZD6244 is a MEK-1 inhibitor. Specifically, AZD6244 inactivates the phosphorylation of ERK1/2.

606143-52-6

Selumetinib, AZD6244, 6- (4-bromo-2-chloroanilino) -7-fluoro-N- (2-hydroxyethoxy) -3-methylbenzimidazole-5-carboxamide

41116105

Inhibitor

Synthetic

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

≥98%

0.005

White to off-white solid

Soluble in DMSO (92 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C)

C17H15BrClFN4O3

457.7

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. Haasbach E., Hartmayer C., & Planz O. (2013) Antiviral Research. 98(2): 319–324.