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AR A014418

GSK-3 kinase inhibitor

Product Specifications

Background

AR A014418 is a highly selective glycogen synthase kinase 3 (GSK-3) inhibitor. GSK-3 is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer′s disease. AR A014418 is cell permeable.

CAS Number

487021-52-3

Product Name Alternative

N- (4-Methoxybenzyl) -N′- (5-nitro-1,3-thiazol-2-yl) urea

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥95% (HPLC)

Weight

0.005

Format

White to off-white solid

Solubility

Soluble in DMSO, methanol, 100% ethanol or ethyl acetate

Molecular Formula

C12H12N4O4S

Molecular Weight

308.3

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bhat R.V., & Budd S.L. (2002) Neuro-Signals. 11(5): 251–261. 2. Gould T.D., Einat H., Bhat R., & Manji H.K. (2004) Int. J. Neuropsychopharmacology (CINP). 7(4): 387–390.

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