AR A014418
GSK-3 kinase inhibitor
Product Specifications
Background
AR A014418 is a highly selective glycogen synthase kinase 3 (GSK-3) inhibitor. GSK-3 is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer′s disease. AR A014418 is cell permeable.
CAS Number
487021-52-3
Product Name Alternative
N- (4-Methoxybenzyl) -N′- (5-nitro-1,3-thiazol-2-yl) urea
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥95% (HPLC)
Weight
0.025
Format
White to off-white solid
Solubility
Soluble in DMSO, methanol, 100% ethanol or ethyl acetate
Molecular Formula
C12H12N4O4S
Molecular Weight
308.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Bhat R.V., & Budd S.L. (2002) Neuro-Signals. 11(5): 251–261.
2. Gould T.D., Einat H., Bhat R., & Manji H.K. (2004) Int. J. Neuropsychopharmacology (CINP). 7(4): 387–390.
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