What is the catalog number for AG 494?

The catalog number for AG 494 is SIH-491-10MG.

What sizes are available for AG 494?

AG 494 is available in the following size(s): 10 mg.

AG 494 is currently made to order / not held in immediate stock. Contact us for lead time.

AG 494

EGFR kinase inhibitor

Product Specifications

Background

AG 494 is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase. It specifically inhibits EGF receptor autophosphorylation and EGF-dependent cell growth.

CAS Number

133550-35-3

Product Name Alternative

AG-494, (E) -2-Cyano-3- (3,4-dihydroxyphenyl) -N-phenyl-2-propenamide

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98% (TLC)

Weight

0.01

Format

Yellow solid

Solubility

Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)

Molecular Formula

C16H12N2O3

Molecular Weight

280.3

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Ben-Bassat H., et al. (1999).J. Pharm. Exp. Ther. 290(3): 1442–1457. 2. Kleinberger-Doron N., Shelah N., Capone R., Gazit A., & Levitzki A. (1998) Exp. Cell . Res. 241(2): 340–351.