ZM447439

Aurora B kinase inhibitor

Product Specifications

Background

ZM447439 is a potent and selective inhibitor of Aurora B kinase. ZM447439 induces cell growth arrest mid-way through mitosis, and therefore effectively activates apoptosis.

CAS Number

331771-20-1

Product Name Alternative

ZM 447439, N-[4-[[6-Methoxy-7-[3- (4-morpholinyl) propoxy]-4-quinazolinyl]amino]phenyl]benzamide

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98% (TLC) ; NMR (Conforms)

Weight

0.01

Format

Orange solid

Solubility

May be dissolved in DMSO (50mg/mL)

Molecular Formula

C29H31N5O4

Molecular Weight

513.6

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Walsby E., Walsh V., Pepper C., Burnett A., & Mills K. (2008) Haematologica. 93(5): 662–669. 2. Kim K.W., et al. (2007) Int. J. Rad.Oncol. Biol. Phy. 67(5): 1519–1525.