Y 27632

Y 27632 is a very potent and selective ROCK1 and ROCK2 inhibitor. Y 27632 is cell permeable and is an ATP competitive inhibitor.

146986-50-7

Y-27632 dihydrochloride, (R) - (+) -trans-N- (4-Pyridyl) -4- (1-aminoethyl) -cyclohexanecarboxamide . 2HCl

41116105

Inhibitor

Synthetic

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

≥98% (HPLC)

0.001

White to pale yellow powder

Soluble in DMSO (25 mg/ml), methanol (25 mg/ml), acetonitrile (<1 mg/ml), dioxan (<1 mg/ml), water (very soluble

C14H23Cl2N3O

320.3

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. Shi J., et al. (2013) Cell Death & Disease, 4: e483.