WHI P131
JAK3 kinase inhibitor
Product Specifications
Background
WHI P131 also known as Janex-1, is a reversible, potent, and specific inhibitor of JAK3. WHI P131 is cell permeable. It has been seen to inhibit glioblastoma cell adhesion and migration, as well as, thrombin-induced platelet aggregation.
CAS Number
202475-60-3
Product Name Alternative
WHI-P131, Janex 1, 4-[ (6, 7-dimethoxy-4-quinazolinyl) amino]-phenol
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98%
Weight
0.05
Format
White to off-white solid
Solubility
Soluble in DMSO (~1 mg/ml), and DMF (~1 mg/ml)
Molecular Formula
C16H15N3O3
Molecular Weight
297.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Sudbeck E.A., et al. (1999) Clin. Cancer Res: J. Am. Asso. Cancer Res. 5(6): 1569–1582.
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