Vatalanib Dihydrochloride
VEGFR Tyrosine Kinase Inhibitor
Product Specifications
Background
Vatalanib Dihydrochloride is an inhibitor of Flk, c-Kit and PDGFR-β. It has been shown to inhibit VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival.
CAS Number
212141-51-0
Product Name Alternative
N- (4-Chlorophenyl) -4- (4-pyridinylmethyl) -1-phthalazinamine dihydrochloride
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cardiovascular System | Cancer Growth Inhibitors | Growth Factor Receptor Inhibitors
Purity
≥96%
Weight
0.05
Format
Solid
Solubility
Soluble in DMSO (30 mg/ml), ethanol (10 mg/ml) with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.Also soluble in methanol, and water ( ≥10 mg/ml )
Molecular Formula
C20H17Cl3N4
Molecular Weight
419.7
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Herbst R.S., Heymach J.V., O'Reilly M. S., Onn A., & Ryan A.J. (2007) Expert Opin. Invest. Drugs. 16(2): 239–249.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![2,3-Diphenyl-5,8-diaminopyrazino[2,3-d]pyridazine](https://cdn.genprice.uk/products/572/334298186221/imageurl/trc-d489500-250mg.webp)
TRC-D489500-250MG 250 mg
2,3-Diphenyl-5,8-diaminopyrazino[2,3-d]pyridazine
Sign In for Pricing
View Details 
PKSH032167-01 10 µg
Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag)
Sign In for Pricing
View Details PKSH032167-02 50 µg
Recombinant Human Carboxylesterase 1/CES1 Protein (His Tag)
Sign In for Pricing
View Details 
BNC881578-500 1x 500 µL
SREBP1 (SREBP1/1578), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details