SU 4312
VEGFR, PDGFR kinase inhibitor
Product Specifications
Background
SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases, including VEGFR-2 (Flk-1, KDR).
CAS Number
5812-07-7
Product Name Alternative
3-[[4- (dimethylamino) phenyl]methylene]-1,3-dihydro-2H-indol-2-one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cardiovascular System | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.005
Format
Orange solid
Solubility
Soluble in DMSO (25 mg/ml)
Molecular Formula
C17H16N2O
Molecular Weight
264.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Zaman G.J., et al. (1999) Biochem. Pharm. 57(1): 57–64.
2. Shimotake J., Derugin N., Wendland M., Vexler Z.S., & Ferriero D.M. (2010) Stroke. 41(2): 343–349.
3. Schultheiss C., et al. (2006) Angiogenesis. 9(2): 59–65.
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