Src I1
Src kinase inhibitor
Product Specifications
Background
SrcI1 is a potent and competitive dual site Src kinase inhibitor. It has been shown as a potent inhibitor of the Src and Lck kinase, as well as, VEGFR2 and c-fms. SrcI1 is cell permeable and can induce apoptosis.
CAS Number
179248-59-0
Product Name Alternative
6,7-Dimethoxy-N- (4-phenoxyphenyl) -4-quinazolinamine, SKI-1, Src Inhibitor-1
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (TLC)
Weight
0.005
Format
Off-white solid
Solubility
Soluble in DMSO (5 mg/ml)
Molecular Formula
C22H19N3O3
Molecular Weight
373.4
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Bain, J., et al. (2007) Biochem. J. 408(3): 297–315. 2. Leung, E. L.H., et al. (2009) Mol. Cancer. Res: MCR. 7(6): 923–932.
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