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Src I1

Src kinase inhibitor

Product Specifications

Background

SrcI1 is a potent and competitive dual site Src kinase inhibitor. It has been shown as a potent inhibitor of the Src and Lck kinase, as well as, VEGFR2 and c-fms. SrcI1 is cell permeable and can induce apoptosis.

CAS Number

179248-59-0

Product Name Alternative

6,7-Dimethoxy-N- (4-phenoxyphenyl) -4-quinazolinamine, SKI-1, Src Inhibitor-1

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98% (TLC)

Weight

0.005

Format

Off-white solid

Solubility

Soluble in DMSO (5 mg/ml)

Molecular Formula

C22H19N3O3

Molecular Weight

373.4

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Bain, J., et al. (2007) Biochem. J. 408(3): 297–315. 2. Leung, E. L.H., et al. (2009) Mol. Cancer. Res: MCR. 7(6): 923–932.

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