K252B
Kinase inhibitor
Product Specifications
Background
K252B is a non-selective, protein kinase inhibitor. It inhibits CaMKII, MYLK, PKA, PKC, and cGKI. It acts by binding to the ATP binding domain of the kinase. K252B is cell permeable.
Product Name Alternative
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid
UNSPSC
41116105
Source
Synthetic
Purity
≥98% (HPLC)
Weight
0.0001
Format
White solid
Solubility
Soluble in DMSO (1 mg/ml) or dimethyl formamide (1 mg/ml)
Molecular Formula
C26H19N3O5
Molecular Weight
453.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Nakanishi S., Matsuda Y., Iwahashi K., & Kase H. (1986) J. Antibiotics 39(8): 1066–1071.
2. Teshima R., et al. (1997) J. Immun. 159(2): 964–969.
3. Knüsel B., et al. (1992) J. Neurochem. 59(2): 715–722.
CAS Number
99570-78-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
