JX 401
P38 MAP kinase inhibitor
Product Specifications
Background
JX 401 is a potent and reversible inhibitor of p38α. Specifically, it binds MAPK p38α. JX 401 is cell permeable.
CAS Number
349087-34-9
Product Name Alternative
1-[2-Methoxy-4- (methylthio) benzoyl]-4- (phenylmethyl) piperidine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (TLC)
Weight
0.05
Format
Off-white solid
Solubility
Soluble in DMSO (20 mg/ml) or ethanol (10 mg/ml)
Molecular Formula
C21H25NO2S
Molecular Weight
355.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Friedmann Y., et al. (2006) Mol. Pharm. 70(4): 1395–1405.
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