JX 401

JX 401 is a potent and reversible inhibitor of p38α. Specifically, it binds MAPK p38α. JX 401 is cell permeable.

349087-34-9

1-[2-Methoxy-4- (methylthio) benzoyl]-4- (phenylmethyl) piperidine

41116105

Inhibitor

Synthetic

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

≥98% (TLC)

0.05

Off-white solid

Soluble in DMSO (20 mg/ml) or ethanol (10 mg/ml)

C21H25NO2S

355.5

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. Friedmann Y., et al. (2006) Mol. Pharm. 70(4): 1395–1405.