GSK690693 Hydrochloride
AKT kinase inhibitor
Product Specifications
Background
GSK690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. It is derived from aminofurazan. It has shown to produce antiproliferative and apoptotic effects in tumor cell lines.
CAS Number
937174-76-0
Product Name Alternative
4-[2- (4-Amino-1,2,5-oxadiazol-3-yl) -1-ethyl-7-[ (3S) -3-piperidinylmethoxy) -1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.025
Format
White to beige solid
Solubility
Soluble to 50 mM in DMSO
Molecular Formula
C21H27N7O3
Molecular Weight
425.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Heerding D.A., et al. (2008) J. Med. Chem. 51(18): 5663–5679. 2. Rhodes N., et al. (2008) Cancer Res. 68(7): 2366–2374.
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