Dorsomorphin
AMPK kinase inhibitor
Product Specifications
Background
Dorsomorphin is a potent and selective and reversible inhibitor of AMP-kinase, doing so in an ATP-competitive manner. It is also a selective inhibitor of Bone morphogenetic protein (BMP) signaling.
CAS Number
866405-64-3
Product Name Alternative
AMPK Inhibitor, Compound C, 6-[4- (2-Piperidin-1-ylethoxy) phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.025
Format
Yellow solid
Solubility
Soluble in DMSO (4 mg/ml, warm)
Molecular Formula
C24H25N5O
Molecular Weight
399.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Vucicevic L., et al. (2011) Autophagy 7(1): 40–50. 2. Yu P.B., et al. (2008). Nat. Chem. Biol. 4(1): 33–41.
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