Doramapimod
P38 MAP kinase inhibitor
Product Specifications
Background
Doramapimod is a highly potent and selective inhibitor of p38α MAPK. It specifically blocks TNFα release.
CAS Number
285983-48-4
Product Name Alternative
JNK Inhibitor XVII, BIRB796, 1-[5-tert-butyl-2- (4-methylphenyl) pyrazol-3-yl]-3-[4- (2-morpholin-4-ylethoxy) naphthalen-1-yl]urea
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥99% (HPLC)
Weight
0.025
Format
White solid
Solubility
Soluble in DMSO
Molecular Formula
C31H37N5O3
Molecular Weight
527.7
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Pargellis C., et al. (2002). Nat Structural Biol. 9(4): 268–272.
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