DMPQ Dihydrochloride
PDGFRβ kinase inhibitor
Product Specifications
Background
DMPQ dihydrochloride is a potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ). It displays > 100-fold selectivity over EGFR tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C.
CAS Number
137206-97-4
Product Name Alternative
5,7-Dimethoxy-3- (4-pyridinyl) quinoline dihydrochloride
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.025
Format
White to beige solid
Solubility
Soluble to 100 mM in water
Molecular Formula
C16H16ClN2O2
Molecular Weight
339.2
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Dolle R.E., et al. (1994) J. Med. Chem. 37(17): 2627–2629.
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