Bml 277
CHK2 kinase inhibitor
Product Specifications
Background
Bml 277 is a highly selective inhibitor of Chk2, making it a useful tool for dissecting the role of Chk2 in cellular signaling.
CAS Number
516480-79-8
Product Name Alternative
Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2- (4- (4-Chlorophenoxy) phenyl) -1H-benzimidazole-5-carboxamide hydrate
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (TLC)
Weight
0.05
Format
Off-white solid
Solubility
Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml)
Molecular Formula
C20H14ClN3O2
Molecular Weight
363.8
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Pereg Y., et al. (2006) Mol. Cell Biol. 26(18): 6819–6831.
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