Bml 277

CHK2 kinase inhibitor

Product Specifications

Background

Bml 277 is a highly selective inhibitor of Chk2, making it a useful tool for dissecting the role of Chk2 in cellular signaling.

CAS Number

516480-79-8

Product Name Alternative

Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2- (4- (4-Chlorophenoxy) phenyl) -1H-benzimidazole-5-carboxamide hydrate

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98% (TLC)

Weight

0.01

Format

Off-white solid

Solubility

Soluble in DMSO (20 mg/ml) or ethanol (20 mg/ml)

Molecular Formula

C20H14ClN3O2

Molecular Weight

363.8

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Pereg Y., et al. (2006) Mol. Cell Biol. 26(18): 6819–6831.

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