AG 879
NGFR kinase inhibitor
Product Specifications
Background
AG879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.
CAS Number
148741-30-4
Product Name Alternative
Tyrphostin AG 879, α-Cyano- (3,5-di-t-butyl-4-hydroxy) thiocinnamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥99% (TLC)
Weight
0.005
Format
Yellow solid
Solubility
Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)
Molecular Formula
C18H24N2OS
Molecular Weight
316.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101. 2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.
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