AG 879

A879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.

148741-30-4

Tyrphostin AG 879, α-Cyano- (3,5-di-t-butyl-4-hydroxy) thiocinnamide

41116105

Inhibitor

Synthetic

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

≥99% (TLC)

0.025

Yellow solid

Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)

C18H24N2OS

316.5

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101. 2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.