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STF-62247

Autophagy inducer

Product Specifications

Background

STF-62247 is a selective cell-permeable inducer of autophagy. This is demonstrated by an induction of large vacuole formation in cells. This observation is especially pronounced in von Hippel-Lindau deficient renal carcinoma cells. Induction of autophagy is also seen in vivo in mice.

CAS Number

315702-99-9

Product Name Alternative

N- (3-Methylphenyl) -4- (4-pyridinyl) -2-thiazolamine

UNSPSC

41116105

Type

Inducer

Source

Synthetic

Field of Research

Cancer | Autophagy

Purity

≥98%

Weight

0.05

Format

Solid

Solubility

Soluble in DMSO (26 mg/ml).

Molecular Formula

C15H13N3S

Molecular Weight

267.35

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Turcotte S., et al. (2008) Autophagy, 4(7): b944-6.

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