BRL-50481
PDE7 inhibitor
Product Specifications
Background
BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2).
CAS Number
433695-36-4
Product Name Alternative
N, N,2-Trimethyl-5-nitro-benzenesulfonamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Neuroscience
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.01
Format
Cream solid
Solubility
May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml)
Molecular Formula
C9H12N2O4S
Molecular Weight
244.26
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91.
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