What is the catalog number for Carnosic acid?

The catalog number for Carnosic acid is SIH-362-50MG.

What sizes are available for Carnosic acid?

Carnosic acid is available in the following size(s): 50 mg.

Is Carnosic acid in stock?

Carnosic acid is currently made to order / not held in immediate stock. Contact us for lead time.

Carnosic acid

PPARγ activator

Product Specifications

Background

Carnosic acid is a benzenediol abietane diterpene naturally extracted from rosemary (Rosmarinus officinalis) and sage (Saliva officinalis). It is a potent antioxidant that inhibits NADH or NADPH induced lipid peroxidation by acting as a free radical scavenger (1). It has been found to increase cellular levels of glutathione (GSH) and prevent 6-hydroxydopamine-induced cell death in SH-SY5Y cells (2). Carnosic acid-stimulation of GSH also inhibits adipocyte differentiation (3). It has also been found to induce apoptosis (4) and inhibit the proliferation and migration of various tumor cell lines (5).

CAS Number

3650-09-7

Product Name Alternative

(4aR,10aS) -5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-1,3,4,9,10,10a-hexahydro-2H-phenanthrene-4a-carboxylic acid

UNSPSC

41116105

Type

Activator

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

≥95% (HPLC) ; NMR (Conforms)

Weight

0.05

Format

Off white to yellow solid

Solubility

Soluble in DMSO (50 mg/ml)

Molecular Formula

C20H28O4

Molecular Weight

332.43

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Schwarz K., Ternes W. (1992) Zeitschrift für Lebensmittel-Untersuchung und –Forschung. 195 (2): 99-103. 2. Chen J.H., et al. Chem. (2012) Res. Toxicol 25:1893. 3. Takahashi T., et al. (2009) Biochem. Biophys. Res. Commun. 382:549. 4. Kar S., et al. (2012) Apoptosis. 17:1735. 5. Barni M.V., et al. (2012) Oncol. Rep. 27:1041.