FK-866 HCl
NAMPT Inhibitor
Product Specifications
Background
Nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis. Extends lifespan of human cells. Cell permeable.
CAS Number
658084-64-1
Product Name Alternative
(E) -N-[4- (1-benzoylpiperidin-4-yl) butyl]-3- (pyridin-3-yl) acrylamide, FK866 hydrochloride hydrate, K22.175
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling
Purity
>98% (TLC), NMR conforms
Weight
0.005
Format
White Solid
Solubility
Soluble in 40 mg/ml Water
Molecular Formula
C24H29N3O2•HCl
Molecular Weight
428
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Hasmann M., et al. (2003) Cancer Res. 63: 7436. 2. van der Veer E., et al. (2007) J. Biol. Chem. 282: 10841.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC401081-100 1x 100 µL
CD45RO (190-2F2.5), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940352-100 1x 100 µL
CD31 / PECAM-1 (158-2B3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC051429-500 1x 500 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF405M conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681485-500 1x 500 µL
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1485), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942298-100 1x 100 µL
Cytokeratin 8/18 (rKRT8.18/1346), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details