Bml-278

A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable.

N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine

41116105

Inhibitor

Synthetic

Cell Signaling | Epigenetics and Nuclear Signaling

>98% (TLC), NMR conforms

0.025

Off-White Solid

Soluble in 5 mg/ml DMSO

C24H25NO4

391.5

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. Mai A., et al. (2009) J. Med. Chem. 52: 5496.