Bml-278
SIRT1 activator
Product Specifications
Background
A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable.
Product Name Alternative
N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling
Purity
>98% (TLC), NMR conforms
Weight
0.025
Format
Off-White Solid
Solubility
Soluble in 5 mg/ml DMSO
Molecular Formula
C24H25NO4
Molecular Weight
391.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Mai A., et al. (2009) J. Med. Chem. 52: 5496.
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