What is the catalog number for 5-Azacytidine?

The catalog number for 5-Azacytidine is SIH-345-250MG.

What sizes are available for 5-Azacytidine?

5-Azacytidine is available in the following size(s): 250 mg.

Is 5-Azacytidine in stock?

5-Azacytidine is currently made to order / not held in immediate stock. Contact us for lead time.

5-Azacytidine

DNA hypomethylation agent

Product Specifications

Background

DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells; induces differentiation of mesenchymal stem cells into cardiomyocytes.

CAS Number

320-67-2

Product Name Alternative

4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2 (1H) -one; Ladakamycin; U-18496; NSC-102816; 5-AzaC

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Epigenetics and Nuclear Signaling | Cancer

Purity

>98% (TLC) ; NMR (Conforms)

Weight

0.25

Format

White Solid

Solubility

Soluble in 25 mg/ml DMSO or 12 mg/ml Water

Molecular Formula

C8H12N4O5

Molecular Weight

244.2

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Schneider-Stock R., et al. (2005) J Pharmacol Exp Ther. 312(2): 525-536. 2. Mikkelsen T.S., et al., (2008) Nature. 454(7200): 49-55. 3. Qian Q., et al., (2012) Stem Cells Dev. 21(1): 67-75.