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SMER3

E3 UB ligase inhibitor

Product Specifications

Background

Specific inhibitor of a yeast SCF family E3 ubiquitin ligase (SCF) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin.

Product Name Alternative

9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one

UNSPSC

41116105

Source

Synthetic

Purity

>98%

Weight

0.05

Format

Yellow Solid

Solubility

Soluble in 75 mM DMSO

Molecular Formula

C11H4N4O2

Molecular Weight

224.18

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Aghajanyy et al. (2010) Nat.Biotechnol. 28: 738.

CAS Number

67200-34-4

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