SMER3
E3 UB ligase inhibitor
Product Specifications
Background
Specific inhibitor of a yeast SCF family E3 ubiquitin ligase (SCF) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Enhancer of rapamycin.
CAS Number
67200-34-4
Product Name Alternative
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.01
Format
Yellow Solid
Solubility
Soluble in 75 mM DMSO
Molecular Formula
C11H4N4O2
Molecular Weight
224.18
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Aghajanyy et al. (2010) Nat.Biotechnol. 28: 738.
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