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DBeQ

P97 inhibitor

Product Specifications

Background

A potent, selective and reversible inhibitor of the AAA-ATP p97 (ATPase associated with diverse cellular activities). Ki=3.2 M. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.

Product Name Alternative

N, N'-Dibenzyl-2,4-quinazolinediamine, JRF 12, N2, N4-dibenzylquinazoline-2,4-diamine, N2, N4-Bis (phenylmethyl) -2,4-quinazo­linediamine

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

>98%

Weight

0.005

Format

Yellow Powder

Solubility

Soluble in 25 mg/ml DMSO

Molecular Formula

C22H20N4

Molecular Weight

340.4

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Chou T.F., et al. 2011 PNAS 108:4834.

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