DBeQ
P97 inhibitor
Product Specifications
Background
A potent, selective and reversible inhibitor of the AAA-ATP p97 (ATPase associated with diverse cellular activities). Ki=3.2 M. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.
Product Name Alternative
N, N'-Dibenzyl-2,4-quinazolinediamine, JRF 12, N2, N4-dibenzylquinazoline-2,4-diamine, N2, N4-Bis (phenylmethyl) -2,4-quinazolinediamine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.005
Format
Yellow Powder
Solubility
Soluble in 25 mg/ml DMSO
Molecular Formula
C22H20N4
Molecular Weight
340.4
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Chou T.F., et al. 2011 PNAS 108:4834.
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