IU1

Selective inhibitor of Usp14 (IC50<4 M). Enhances proteasome activity and substrate proteolysis. Cell permeable.

314245-33-5

1-[1- (4-Fluoro-phenyl) -2,5-dimethyl-1H-pyrrol-3-yl]-2-pyrrolidin-1-yl-ethanone

41116105

Inhibitor

Synthetic

Cancer | Apoptosis

>98%

0.05

Beige Solid

Soluble in 30 mg/ml DMSO, 15 mg/ml Ethanol

C18H21FN2O

300.4

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

1. Lee B.H., et al. (2010) Nature 467: 1179. 2. Lee B.H., et al. (2010) Mol. Cell. Proteomics 10: R1100003871.