A-803467
NaV1.8 blocker
Product Specifications
Background
A selective blocker of Nav1.8 channels. A-803467 potently reduced thermal hyperalgesia in inflammatory models of pain and mechanical allodynia in neuropathic models of pain, but was relatively ineffective in a skin-incision model of postoperative pain, a chemotherapy induced pain, and in visceral pain (1).
CAS Number
944261-79-4
Product Name Alternative
5- (4-Chlorophenyl) -N- (3,5-dimethoxyphenyl) -2-furamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Neuroscience | Ion Channels | Sodium Channels
Purity
>98%
Weight
0.05
Format
Beige Solid
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Rush A.M., Cummins T.R. (2007) Mol Interv. 7(4): 192-195.
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