HC-030031
TRPA1 blocker
Product Specifications
Background
Selective TRPA1 channel blocker that antagonizes AITC-and formalin-evoked calcium influx. Doe not block currents mediated by TRPV1, V3, V4, hERG or Nav1.2 channels (1-2).
CAS Number
349085-38-7
Product Name Alternative
2- (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl) -N- (4-isopropylphenyl) acetamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels
Purity
>98%
Weight
0.01
Format
White solid
Solubility
Soluble to 100 mM in DMSO
Molecular Formula
C18H21N5O3
Molecular Weight
355.39
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. McNamara C.R., et al. (2007) Proc Natl Acad Sci USA. 104(33): 13525-13530. 2. Taylor-Clark T.E., et al. (2008) Mol Pharmacol. 73(2): 274-281.
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