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HC-030031

TRPA1 blocker

Product Specifications

Background

Selective TRPA1 channel blocker that antagonizes AITC-and formalin-evoked calcium influx. Doe not block currents mediated by TRPV1, V3, V4, hERG or Nav1.2 channels (1-2).

Product Name Alternative

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide

UNSPSC

41116105

Source

Synthetic

Purity

>98%

Weight

0.01

Format

White solid

Solubility

Soluble to 100 mM in DMSO

Molecular Formula

C18H21N5O3

Molecular Weight

355.39

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. McNamara C.R., et al. (2007) Proc Natl Acad Sci USA. 104(33): 13525-13530. 2. Taylor-Clark T.E., et al. (2008) Mol Pharmacol. 73(2): 274-281.

CAS Number

349085-38-7

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