What is the catalog number for Astemizole?

The catalog number for Astemizole is SIH-302-50MG.

What sizes are available for Astemizole?

Astemizole is available in the following size(s): 50 mg.

Is Astemizole in stock?

Astemizole is currently made to order / not held in immediate stock. Contact us for lead time.

Astemizole

Herg channel blocker

Product Specifications

Background

Astemizole is a second generation antihistamine drug which has a long duration of action. It binds to histamine H1-receptor sites in the gastrointestinal tract, uterus, blood vessels and bronchial muscle. It does not cross the blood-brain barrier, and the binding is primarily in the peripheral nervous system (1). It is metabolized by CYP3A4 (2).

CAS Number

68844-77-9

Product Name Alternative

1- (4-Fluorobenzyl) -N-{1-[2- (4-methoxyphenyl) ethyl]-4-piperidinyl}-1H-benzimidazol-2-amine, Hismanal

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Neuroscience | Ion Channels

Purity

>98%

Weight

0.05

Format

White solid

Solubility

Soluble to 100 mM in DMSO and to 25 mM in ethanol

Molecular Formula

C28H31FN4O

Molecular Weight

458.57

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Laduron P.M., Janssen P.F., Commeren W. and Leysen J.E. (1982) Mol Pharmacol. 21(2): 294-300. 2. Maysumoto S., Yamazoe Y. (2001) Br. J Clin Pharamcol. 51(2): 133-142.