Zerumbone
NF-κB kinase inhibitor
Product Specifications
Background
Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Has no cytotoxic effect on normal cells. Cell permeable. Natural sesquiterpene ketone isolated from Zingiber sp.
CAS Number
471-05-6
Product Name Alternative
(2E,6E,10E) -2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.05
Format
White to off-white solid
Solubility
Soluble in DMSO (≥10 mg/ml)
Molecular Formula
C15H22O
Molecular Weight
218.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Leu J.L., et al. (2009) Mol Cell. 36:15.
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