Zerumbone
NF-κB kinase inhibitor
Product Specifications
Background
Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Has no cytotoxic effect on normal cells. Cell permeable. Natural sesquiterpene ketone isolated from Zingiber sp.
Product Name Alternative
(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
UNSPSC
41116105
Source
Synthetic
Purity
>98%
Weight
0.01
Format
White to off-white solid
Solubility
Soluble in DMSO (≥10 mg/ml)
Molecular Formula
C15H22O
Molecular Weight
218.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Leu J.L., et al. (2009) Mol Cell. 36:15.
CAS Number
471-05-6
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