Resveratrol

Background

Resveratrol is a stilbenoid and a phytoalexin produced naturally by several plants. Its effects are numerous and include anti-cancer (1), anti-inflammatory (2), anti-fungal and has other beneficial cardiovascular effects. It has been proposed that Mn SOD is increased by the pathwayRESV-SIRT1/Nad+- FOXO3a- MnSOD (3). In terms of its anti-cancer properties, resveratrol modulates the transcription factor NF-KB and inhibition of the cytochrome P450 enzyme (1, 4). It also enhances hippocampal neurogenesis.

Product Name Alternative

5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol

UNSPSC

41116105

Source

Synthetic

Purity

>98%

Weight

0.5

Format

Off-White Solid

Solubility

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Molecular Formula

C14H12O3

Molecular Weight

228.25

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Leiro J., et al. (2005) Int Immunopharm. 5(2): 393-406. 2. Gentilli M., et al. (2001) Life Sciences. 68(11): 1317-1321. 3. Robb E.L., et al. (2008) Biochem Biophys Res Commun. 367(2): 406-412. 4. Chun Y.J., Kim M.Y., Guengerich F.P. (1999) Biochem Biophys Res Commun. 262(1): 20-24.

CAS Number

501-36-0

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