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Caffeic Acid Phenethyl Ester (CAPE)

NFkB Inhibitor

Product Specifications

Background

CAPE , an active component of propolis from honeybee hives is known to have antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral properties (1). It specifically inhibits NF-κB activation and inhibits the growth of transformed cells (1). Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.

CAS Number

104594-70-9

Product Name Alternative

2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate, Caffeic acid phenethyl ester

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cancer | Apoptosis

Purity

>98%

Weight

0.05

Format

Off-White Solid

Solubility

Soluble to 100 mM in DMSO, acetone, ethanol, methanol, acetonitrile

Molecular Formula

C17H16O4

Molecular Weight

284.31

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. (1996) Proc Natl Acad Sci USA. 93(17): 9090-9095.

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