Caffeic Acid Phenethyl Ester (CAPE)
NFkB Inhibitor
Product Specifications
Background
CAPE , an active component of propolis from honeybee hives is known to have antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral properties (1). It specifically inhibits NF-κB activation and inhibits the growth of transformed cells (1). Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.
CAS Number
104594-70-9
Product Name Alternative
2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate, Caffeic acid phenethyl ester
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.25
Format
Off-White Solid
Solubility
Soluble to 100 mM in DMSO, acetone, ethanol, methanol, acetonitrile
Molecular Formula
C17H16O4
Molecular Weight
284.31
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. (1996) Proc Natl Acad Sci USA. 93(17): 9090-9095.
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