What is the catalog number for Trichostatin A?

The catalog number for Trichostatin A is SIH-254-5MG.

What sizes are available for Trichostatin A?

Trichostatin A is available in the following size(s): 5 mg.

Is Trichostatin A in stock?

Trichostatin A is currently made to order / not held in immediate stock. Contact us for lead time.

Trichostatin A

HDAC inhibitor

Product Specifications

Background

Trichostatin A is an antifungal and selectively inhibits the class I and II mammalian histon deacetlyase families of enzymes (1). TSA inhibits the eukayotic cell cycle during the beginning of the growth stage. It can be used to alter gene expression but interfering with the removal of acetyl groups thereby altering the ability of DNA transcription factors to access the DNA inside chromatin (2). It also has anti-cancer properties (3).

CAS Number

58880-19-6

Product Name Alternative

(2E,4E,6R) -7-[4- (Dimethylamino) phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cancer | Apoptosis | Cancer Growth Inhibitors | HDAC Inhibitors

Purity

>98%

Weight

0.005

Format

Beige Solid

Solubility

Soluble to 10 mM in ethanol and to 50 mM in DMSO

Molecular Formula

C17H22N2O3

Molecular Weight

302.37

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Vanhaecke T., Papeleu P., Elaut G., Rogiers V. (2004) Curr Med Chem. 11(12): 1629-1643. 2. Yoshida, et al. (1990) J Biol Chem. 165: 17174. 3. Drummond D.C., et al. (2005) Annu Rev Pharmacol Toxicol. 45: 495-528.