Staurosporine
Protein kinase inhibitor
Product Specifications
Background
Staurosporine is a broad spectrum protein kinase inhibitor with activities ranging from anti-fungal to anti-hypertensive (1). Staurosporine is a typical ATP-competitive kinase inhibitor that binds to many kinases with high affinity, but with little selectivity (2).
CAS Number
62996-74-1
Product Name Alternative
(2S,3R,4R,6R) -3-Methoxy-2-methyl-4- (methylamino) -29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.00025
Format
Pale Yellow Solid
Solubility
Soluble to 50 mM in DMSO
Molecular Formula
C28H26N4O3
Molecular Weight
466.54
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Ruegg U.T., and Burgess G.M. (1989) Trends in Pharm Science. 10(6): 218-220. 2. Karaman M.W., et al. (2008) Nat. Biotechnol. 26(1): 127-132.
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