Deguelin
Akt inhibitor
Product Specifications
Background
Deguelin is a rotenoid, and a naturally occurring insecticide. Deguelin displays anti-cancer activity by inhibiting the growth of pre-cancerous and cancerous cells (1). High doses may have negative effects on the heart, lungs and nerves however. Deguelin has also been shown to have a correlation with Parkinson's disease in rats (2).
CAS Number
522-17-8
Product Name Alternative
(7aS,13aS) -9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7 (7aH) -one
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.01
Format
Cream Solid
Solubility
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Molecular Formula
C23H22O6
Molecular Weight
394.42
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Lee H.Y. (2004) Biochem Pharmacol. 68(6): 1119-1124. 2. Caboni P., et al. (2004) Chem Res. Toxicol. 17(11): 1540-1548.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC682032-500 1x 500 µL
Biotin (Vitamin B7 or Vitamin H) (BTN/2032R), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041077-500 1x 500 µL
Cytokeratin, LMW (KRTL/1077), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUM2200-50 1x 50 µL
Cytokeratin 7 (Glandular and Transitional Epithelial Marker) (KRT7/2200), 1mg/mL
Sign In for Pricing
View Details 